Product Name : | 5-Bromoindole-2-carboxylic acid | ||
Synonyms : |
| ||
Smiles : | O=C(O)C1=CC=2C=C(Br)C=CC2N1 | ||
InChI | InChI=1S/C9H6BrNO2/c10-6-1-2-7-5(3-6)4-8(11-7)9(12)13/h1-4,11H,(H,12,13) | ||
InChIKey | YAULOOYNCJDPPU-UHFFFAOYSA-N | ||
CAS Number : | 7254-19-5 | ||
Molecular Formula : | C9H6BrNO2 | Molecular Weight : | 240.05 |
Specifications: | |
Appearance | White to Light yellow to Light orange powder to crystal |
Purity (GC) | Min. 98.0 % |
Purity(Neutralization titration) | min. 98.0 % |
Properties: | |
Melting Point | 285 °C – 287 °C |
Boiling Point (Predicted) | 470.9±25.0 °C |
Density (Predicted) | 1.838±0.06 g/cm3 |
Purity / Analysis Method | >98.0%(T) |
Molecular Formula / Molecular Weight | C9H6BrNO2= 240.06 |
Physical State (20 deg.C) | Solid |
Store Under Inert Gas | Store at ambient temperature under inert gas |
Condition to Avoid | Heat Sensitive |
CAS Number | 7254-19-5 |
Reaxys Registry Number | 153253 |
PubChem Substance ID | 135727124 |
MDL Number | MFCD00022705 |
» General Information: |
|
Purity / Analysis Method | >98.0%(T) |
Molecular Formula / Molecular Weight |
C9H6BrNO2= 240.06 |
Physical State (20 deg.C) | Solid |
Store Under Inert Gas | Store at ambient temperature under inert gas |
Condition to Avoid | Heat Sensitive |
CAS RN | 7254-19-5 |
Reaxys Registry Number | 153253 |
PubChem Substance ID | 135727124 |
MDL Number | MFCD00022705 |
» Specifications: |
|
Appearance | White to Light yellow to Light orange powder to crystal |
Purity (GC) | Min. 98.0 % |
Purity(Neutralization titration) | Min. 98.0 % |
» Properties: |
|
Melting Point | 285 °C – 287 °C |
Boiling Point (Predicted) | 470.9±25.0 °C |
Density (Predicted) | 1.838±0.06 g/cm3 |
Application:
The indole backbone of 5-Bromoindole-2-carboxylic acid is encountered in a class of N-heterocyclic compounds with physiological and pharmacological effects such as anti-cancer, anti-diabetic, and anti-HIV. These compounds are becoming increasingly popular in organic, medicinal, and pharmaceutical research. Nitrogen compounds’ hydrogen bonding, dipole- dipole interactions, hydrophobic effects, Van der Waals forces, and stacking interactions have increased their relevance in pharmaceutical chemistry due to their improved solubility. Indole derivatives, such as carbothioamide, oxadiazole, and triazole, have been reported to act as anti-cancer drugs due to their ability to disrupt the mitotic spindle and prevent human cancer cell proliferation, expansion, and invasion.
Description:
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